1. Onconic Therapeutics Q2 2025 Performance: What Happened?

Onconic Therapeutics reported revenue of ₩9.4 billion and operating profit of ₩1.1 billion in Q2 2025, marking a return to profitability. However, the company recorded a net loss of ₩0.1 billion. While Zastaprazan sales fueled the positive turnaround, the net loss raises questions for investors.

2. Drivers of Performance: Why These Results?

  • Zastaprazan Sales Growth: Following approval for the treatment of gastric ulcers, Zastaprazan has become a key growth driver, accounting for ₩16.4 billion of the ₩18.6 billion in H1 2025 revenue.
  • Nesuparib Clinical Development: Ongoing Phase 1b/2 and investigator-initiated Phase 2 trials for Nesuparib provide long-term growth potential.
  • Technology Licensing Agreements: Deals for Zastaprazan in China, India, and South America contributed ₩2.18 billion to H1 2025 revenue, diversifying income streams.

3. Outlook and Investment Strategy: What’s Next?

In the short term, investors should monitor market reaction to the Q2 net loss. Volatility may increase depending on Zastaprazan’s market penetration and Nesuparib clinical trial results. Longer term, market share expansion for Zastaprazan and successful clinical outcomes for Nesuparib will be key drivers of value creation.

4. Key Investor Takeaways: What to Watch

  • Zastaprazan market penetration and sales growth
  • Nesuparib Phase 2 clinical trial results
  • Further technology licensing agreements
  • Improvement in operating margin and sustained net income profitability